28 research outputs found

    Leadership formation : interpreting experience

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    In this essay we look at leadership development differently, through the lens of philosophical hermeneutics. We show how three aspects of philosophical hermeneutics - focused on accumulating experience of interpretation, engaging in dialogue and interpreting experience - connect with insights from the leadership development literature and lead to principles for a process of leadership formation. The process we describe explains how formation: extends historically through connection with traditions; involves processes of careful, situated dialogic engagement; and encompasses aesthetic engagement with experience in each event of interpretation. Building on these insights, we derive practical implications for educational policy and practice and develop theoretical implications for leadership development debates.PostprintPeer reviewe

    The organization of interdisciplinary research : modes, drivers and barriers

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    Although the role and management of interdisciplinary research in knowledge development has received plenty of attention in recent years ambiguity remains, often hindering management efforts. To address this issue, this paper provides an integrated review of extant literature on interdisciplinary research. It focuses on integration processes and the main drivers and barriers to different modes of collaborative interdisciplinary research. We propose a different approach to considering interdisciplinary integration, based on two factors: the type of knowledge integration, and the durability of the context of that integration. As a result we characterize four modes of interdisciplinary integration. We then consider how different groups of drivers of, and barriers to, interdisciplinary research affect those types of integration. Overall the paper provides an integrated perspective for researchers, managers and policy makers concerned with understanding the organization of interdisciplinary research.PostprintPeer reviewe

    Exposing practical, psychological and pedagogical shadow sides of experiential learning

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    This paper is based first-person experience with Experiential Learning (EL) practices in an undergraduate introductory management course. We consider how a challenging EL activity, based on volunteering during recovery from a catastrophic flood event, exposed three shadow sides of EL. These shadow sides of EL, that often remain hidden to educators, are practical, psychological and pedagogical. We provide a characterisation of each of these shadow sides and outline strategies for managing them. We also discuss the general applicability of our insights, including tentative theoretical extensions to Kolb’s (1984) EL theory. We conclude by considering the potential for the shadow sides of EL to emerge in circumstances that are less confronting and extreme than those encountered by our students.PostprintPeer reviewe

    Non-Standard Errors

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    In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence-generating process (EGP). We claim that EGP variation across researchers adds uncertainty: Non-standard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for better reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants

    Whole-genome sequencing reveals host factors underlying critical COVID-19

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    Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2–4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

    Whole-genome sequencing reveals host factors underlying critical COVID-19

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    Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

    The organization of interdisciplinary research:modes, drivers and barriers

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    Although the role and management of interdisciplinary research in knowledge development has received plenty of attention in recent years ambiguity remains, often hindering management efforts. To address this issue, this paper provides an integrated review of extant literature on interdisciplinary research. It focuses on integration processes and the main drivers and barriers to different modes of collaborative interdisciplinary research. We propose a different approach to considering interdisciplinary integration, based on two factors: the type of knowledge integration, and the durability of the context of that integration. As a result we characterize four modes of interdisciplinary integration. We then consider how different groups of drivers of, and barriers to, interdisciplinary research affect those types of integration. Overall the paper provides an integrated perspective for researchers, managers and policy makers concerned with understanding the organization of interdisciplinary research. <br/

    Computerberechnung von Phasendiagrammen unter besonderer Beruecksichtigung chemischer und magnetischer Ordnungsreaktionen

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    With 81 refs.SIGLECopy held by FIZ Karlsruhe; available from UB/TIB Hannover / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

    Getting on with field research using participant deconstruction

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    This paper adds to the repertoire of field research methods through developing the technique of ‘participant deconstruction’. This technique involves research participants challenging and re-interpreting organizational texts through the application of orienting, disorienting and re-orienting deconstructive questions. We show how participant deconstruction complements existing strategies for ‘getting on’ with field research – cultivating relationships, developing outsider knowledge and mobilising insider knowledge – by facilitating research participants’ questioning and challenging of organizational texts and thus opening up alternative latent understandings, illuminating concealed meanings and supporting reflexivity for participants and researchers, thereby opening up fruitful lines of inquiry. We illustrate the application of the technique with examples drawn from healthcare research projects. Through gathering further practitioner feedback from a variety of alternative contexts, we go on to demonstrate the potential application of participant deconstruction in a range of field contexts, by different types of practitioners undertaking deconstructive readings of a wide variety of organizational texts. We also offer suggestions for further research to extend the technique

    Identity-in-the-work and musicians’ struggles:the production of self-questioning identity work

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    This article is based on data from a research study financially supported by the ESRC [RES-331-27-0065].Identity work is widely regarded as a process through which people strive to establish, maintain or restore a coherent and consistent sense of self. In the face of potential disruptions of, or threats to, their identities, people seek to salvage their sense of self by resolving tensions and restoring consistency. In contrast to the current identity work literature, this research indicates that identity work is not always about seeking resolution and moving on, but sometimes about continuing struggles which do not achieve a secure sense of self. This paper seeks to elaborate the understanding of unresolved identity work by exploring three contexts of the everyday practice of indie musicians. An analysis of how they struggle to construct acceptable versions of their selves as songwriter, bandleader and front(wo)man allows us to develop the conceptualization of self-questioning (as opposed to self-affirmative, resolution-oriented) identity work.PostprintPeer reviewe
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